MI Profile for Internationalchange location
MI Profile is a multi-platform, solid tumor biomarker analysis for therapeutic decision support and clinical trials matching. Technologies used to asses DNA, RNA and Protiens include, Next-Generation Sequencing DNA/RNA (also called MI Tumor Seek), Pyro Sequencing, Fragment Analysis, Immunohistochemistry and Chromogenic in situ Hybridization.
The information below details the biomarkers tested and technology platforms utilized by tumor type.
In certain instances, some biomarkers included in MI Profile or genes ordered individually will not associate with commercially available cancer therapies or clinical trials.
For PD-L1 IHC testing, Dako antibody 22c3 or antibody SP-142 are available upon request.
- For all cases with an MSI result of equivocal, MMR IHCs (MLH1, MSH2, MSH6, PMS2) will be performed.