Comprehensive Genomic Profiling PLUS
A better foundation for molecular intelligence with CGP+.
Comprehensive Genomic Profiling PLUS
Personalize treatment options and uncover novel molecular insights through comprehensive interrogation of important DNA, RNA and Proteins.
Enable the delivery of precision medicine. Read
Proven Clinical Utility
Research studies continue to demonstrate the clinically utility and actionability of multi-platform profiling with Caris Molecular Intelligence.
Extend overall survival. Read
Molecular Information Powerhouse
Enhance R&D innovation and maximize commercial value with advanced and comprehensive molecular insights that can be customized to your needs.
Discover our molecularly informed solutions. Read
Physicians
Our Comprehensive Genomic Profiling PLUS (CGP+) approach to tumor profiling assess DNA, RNA and Proteins to reveal a molecular blueprint to guide more precise and individualized treatment decisions. With results back in about 8 days, we’ll help you find better answers when you need it most.
Biopharma Services
As a leading life sciences company at the forefront of precision medicine, Caris Life Sciences® is helping our partners drive R&D innovation and maximize commercial value with extensive molecular and clinical information with diverse testing capabilities.
Tumor Profiling:
Multi-platform, solid tumor biomarker analysis for therapeutic decision support and clinical trials matching. The technology platforms used and biomarkers tested may vary based on the tumor type submitted.
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Next-Generation Sequencing analysis for DNA mutations, copy number alterations, insertions/deletions, genomic signatures (microsatellite instability, tumor mutational burden), and RNA fusion analysis for select lineages.
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“Caris Life Sciences was founded because of an idea - that personalized and precise information will improve healthcare for everyone.”
David D. Halbert
Chairman and CEO
"Over the last decade it has become clear that cancer is an insidious enemy exploiting a multitude of different pathways to escape our treatments. Each patient requires a more intelligent and comprehensively designed treatment strategy to enable them to fight their disease most effectively."
David Spetzler, MS, MBA, PhD
President and Chief Scientific Officer
"The essence of any clinical decision should be to use the best possible information for the most rational choice to benefit the patient."
George Poste, DVM, PhD, FRC Path, FHS
Vice Chairman, Caris Life Sciences
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Clinical Cases
Established in 2008, Caris is the first and most experienced tumor profiling provider.
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Tests Completed
Leveraging multiple technologies to interrogate DNA, RNA and Proteins.
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Calendar Days
The current time it takes for us to deliver molecular insights to personalize medicine (most frequent turnaround time). Turnaround time for Caris profiling is 8-14 days.
Latest News
Caris Life Sciences Expands Management Team
June 26, 2018
Meeting the needs of a complex and growing market Brian Brille, experienced financial services executive joins as Vice Chairman, leading corporate and business development, M&A and capital markets Seasoned healthcare executives Michael Sullivan and Nicholas Nelson appointed as Chief Commercial Officer and Chief Business Officer, respectively IRVING, Tex., June 26, 2018 – Caris Life Sciences®, … Continued
Caris Life Sciences Presents Data Demonstrating the Ability of ADAPT Biotargeting System to Identify Responders and Non-Responders in a Phase III Pancreatic Cancer Study
June 21, 2018
Leveraging ADAPT Biotargeting System would have significantly increased the probability of success Data presented at the ESMO World Congress on Gastrointestinal Cancer 2018 IRVING, Tex., June 21, 2018 – Caris Life Sciences®, a leading innovator in molecular science focused on fulfilling the promise of precision medicine, today announced new data supporting the use of its … Continued
Bloomberg: Genetic-Sequencing Firm CEO With Jack Welch Aura Mulls New IPO
June 6, 2018
The following article appeared in Bloomberg: Genetic-Sequencing Firm CEO With Jack Welch Aura Mulls New IPO. Cristin Flanagan. June 6, 2018. David Halbert says he never missed or lowered his forecasts as the former head of a publicly traded company and grew earnings per share for investors quarter after quarter. Immediately, one of the Street’s most celebrated … Continued
Order Profiling Now
Reliable molecular information that serves as a molecular blueprint to personalize cancer therapy and improve care.
MI Profile Report
Caris Molecular Intelligence (MI Profile) reports are built to maximize clinical utility in an easy-to-interpret format. We understand that clinicians need treatment information fast. That’s why the top page of every report presents all potentially relevant, actionable clinical information in an easy-to-digest summary.
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FAQs
Caris Molecular Intelligence enables the delivery of precision medicine by providing oncologists with clinically actionable and individualized cancer treatment information to help personalize cancer care. Our Comprehensive Genomic Profiling PLUS (CGP+) approach to assess DNA, RNA and Proteins reveals a molecular blueprint to guide more precise and individualized treatment decisions.
Clinical research studies continue to demonstrate the utility of Caris Molecular Intelligence and have demonstrated its positive effect on the overall survival (OS) outcomes of cancer patients. Two studies, one conducted on a large group of patients suffering from refractory, metastatic, or rare cancers in 2015 and the other on a cohort of ovarian cancer patients in 2014, showed that patients treated according to Caris Molecular Intelligence results experienced between 9-14 months longer survival and received one fewer cancer drugs (avoiding potential toxicities and extra cost of therapy), vs patients not treated according to Caris recommendations. Learn more.
Caris Molecular Intelligence provides therapeutic insights designed to aid oncologists in personalizing cancer therapies for their patients. Caris Molecular Intelligence allows physicians to:
• Navigate among therapies with potential benefit;
• Identify therapies that may not have been considered;
• Determine drugs with potential lack of benefit (avoiding unnecessary toxicities and costs); and
• Match patients to clinical trials.
Based on the clinical literature, biomarker and therapeutic associations are best analyzed by specific technologies looking for explicit genomic and proteomic aberrations. As such, Caris examines DNA, RNA and proteins to decode a patient’s tumor and provide a more comprehensive tumor assessment. One technology may not be sufficient or clinically appropriate to provide an integrated picture of a tumor’s biology. Learn more about our profiling technologies.
The ordering physician will receive the results of the patient’s tumor analysis in a clinically actionable report. There are 3 ways to access patient reports:
• MI Portal: On-demand access to interactive reports, plus electronic ordering and many other extra features;
• Email: Fully interactive reports delivered in real-time, right to your inbox (MI Portal account required to enroll in email report deliver);
• Fax: Reports delivered in real-time — due to the limited nature of faxing, however, interactive report features and color options are unavailable.
View a sample report.
After the specimen and required paperwork have been received by Caris Life Sciences, the ordering physician will receive the report in approximately 8-14 days. International cases range from 10-21 days due to additional shipping/customs requirements.
Yes, every report includes the Clinical Trials Connector™ at no additional cost. The Clinical Trials Connector a clinical trials matching service that identifies open and enrolling clinical trials tailored to the lineage and/or biomarker profile of the patient’s tumor.
Caris Molecular Intelligence is performed in our state-of-the-art, 66,000 sq-ft laboratory in Phoenix, Arizona. Our laboratory holds the industry’s strictest quality and compliance accreditations, including ISO 15189, CAP, CLIA, NY State and CE Mark.
Yes, Caris Molecular Intelligence is typically reimbursed by Medicare and other insurance providers. Caris Life Sciences will bill the patient’s insurance company, and the patient is typically responsible for co-payments, co-insurance and/or the deductible, as required by law.
Depending on the profile ordered, the number of markers analyzed and technologies used, the cost will differ among the various tumor profiling options. Learn more.