Components of a Report

With convenient online access, MI Profile reports from Caris provide the clinically relevant information oncologists need to individualize cancer treatment.

Molecular Intelligence Summary

Each MI Profile report provides a summary listing of agents associated with potential clinical benefit, agents associated with potential lack of clinical benefit, and relevant, open clinical trials, as well as patient-specific information such as biomarker expression levels and pathologic diagnosis.

Detailed Summary

A breakdown of biomarker results used to provide a list of agents associated with potential clinical benefit and a list of agents associated with potential lack of clinical benefit. This information includes:

  • Agents associated with specific biomarkers
  • Method/technology used for biomarker analysis
  • Biomarker result
  • Clinical association (with benefit or with lack of benefit)
  • Level of evidence associated with agent/ biomarker combinations

Clinical Trials Connector

The Clinical Trials Connector identifies open, relevant clinical trials based on the patient’s tumor type and biomarkers expressed. Each Caris report provides additional information related to the trials, including: protocol number, study title, phase, featured drug and biomarker, and locations accepting subjects.

Literature Level of Evidence and Biomarker Descriptions

An analysis of scientific literature to provide a level of evidence supporting recommended agents associated with potential clinical benefit and agents associated with potential lack of clinical benefit.

Detailed Report of all Analyses Performed

A breakdown of specific results for all biomarkers as analyzed by IHC, FISH and CISH, PCR, DNA sequence analysis and Next-Generation Sequencing.

A description of each of the relevant biomarkers, as well as a summary of these biomarkers’ roles in cancer biology and treatment.

Sample Report