Molecular Intelligence™ at Work

Caris Life Sciences® Molecular Intelligence Service offers complete tumor analysis coupled with an extensive clinical literature review. By matching potential therapies to patient-specific biomarker information, Caris Molecular Intelligence provides the clinically relevant, patient-specific information doctors need to individualize cancer treatment.

Sophisticated Tumor Interrogation and Analysis

  • DNA sequencing, polymerase chain reaction (PCR) and next-generation sequencing* — identify mutations
  • Fluorescence (FISH) and chromogenic (CISH) in situ hybridization – detect gene rearrangements and gene copy number variations
  • Immunohistochemistry (IHC) – determines a biomarker’s level of protein expression

Extensive Clinical Literature Assessment

  • Maintains an up-to-date repository of the world’s most relevant clinical literature
  • Caris has reviewed over 100,000 clinical literature manuscripts
  • Reviews and evaluates studies based on the strength of clinical evidence supporting associations between biomarkers and treatments
  • Performed by disease-specific clinical advisory boards and a team of Ph.D. scientists, oncologists and pathologists
* Certain tests may require a New York State non-permitted laboratory test request approval.