carboplatin

Carboplatin is an alkylating agent that works by attaching an alkyl group to the guanine base of DNA. Because cancer cells often proliferate more quickly and are less able to correct DNA errors than normal cells, they are more sensitive to DNA damage caused by alkylation. Carboplatin is indicated* for the initial treatment of ovarian cancer that has spread beyond the ovaries in combination with other approved chemotherapy drugs. Carboplatin is also indicated for palliative treatment in patients with ovarian cancer that has recurred after therapy with other drugs.

*Please refer to full prescribing information/package insert for precise indications.

Associated Tumor Types

Associated Biomarkers

Associated Signaling Pathways

Content provided for information purposes only and does not necessarily reflect the markers included in the Caris Molecular Intelligence Service. References on file and available upon request.